Scientific research in Menoufia medicine; Confirms the presence of cancer cells floating in the blood of ovarian cancer patients, which helps in early diagnosis, development of treatment methods and follow-up

A scientific research carried out by Dr. Mohamed Shalibi to obtain a doctorate degree in obstetrics and gynecology from the Faculty of Medicine, Menoufia University, confirmed the presence of cancer cells floating in the blood of ovarian cancer patients, which help in the early diagnosis of ovarian tumors and the development of treatment and follow-up methods. The researcher conducted a study to discover the presence of rotating cancer cells. In the blood of patients with ovarian cancer of different stages, and whether these cells, if present, are related to the stages of tumor development compared to tumor markers, and whether it is possible to use these cells in diagnosing the tumor and determining surgical and therapeutic intervention compared to tumor markers used in ovarian cancer. As the circulating cells in the blood are their source from the tumor after their separation from it under the pressure of the increasing growth of the tumor. Most of these cells are tumor stem cells and are able to grow in other parts of the body when they reach them with the bloodstream. Therefore, it is considered a great responsibility for the spread of the tumor on the one hand and its reappearance on the other hand. The researcher used flow cytometry technology at the Center of Excellence for Cancer Research at Tanta University.

The results of the study concluded that these circulating cancer cells are already present in the blood of patients with malignant, not benign, ovarian tumors, as their numbers were directly proportional to the stage of tumor progression.

The results of the study concluded that these circulating cancer cells are already present in the blood of patients with malignant, not benign, ovarian tumors, as their numbers were directly proportional to the stage of tumor progression.

The letter recommended the use of these cells in predicting the stage of the tumor and determining the surgical and therapeutic intervention. The study also recommended the need to expand the study to a larger number of patients, in cooperation between Egyptian universities, to come up with a more statistically accurate recommendation.
This research is an important scientific cooperation between Menoufia University represented by the Department of Obstetrics and Gynecology at the Faculty of Medicine, Menoufia University and the Center of Excellence for Cancer Research at the International Teaching Hospital at Tanta University. Where the practical part of the thesis was conducted at the Center of Excellence for Cancer Research, Tanta University
The research is under the supervision of Dr. Mohamed Salama Gad, Professor of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Dr. Alaa Al-Halabi, Professor in the Department, and Prof. Dr. Mohamed Labib Salem, Professor of Immunology at Tanta University.
The external judging committee consisted of Dr. Sobhi Abul-Louz and Dr. Mohamed Kandil, Head of the Department of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University. And the internal governance committee from Dr. Muhammad Salama Gad and Dr. Muhammad Labib Salem, professor of immunology at the Faculty of Science, Tanta University