عنوان البحث | ملخص البحث | Research Abstract |
Conversion of stem cells to cancer stem cells: undercurrent of cancer initiation | | Cancer stem cells (CSCs) also known as cancer-initiating cells (CIC), are responsible for the sustained and uncontrolled growth of malignant tumors and are proposed to play significant roles in metastasis and recurrence |
A model of CSC converted from iPSC in the conditioned medium of HCC paving the way to establish HCC CSC | | Hepatocellular carcinoma (HCC) represents the major histological subtype, accounting for 70%–85% of cases of primary liver cancer. Liver CSCs sustain their self-renewal remains largely unknown |
Five Fibrosis Biomarkers Together with Serum Ferritin Level to Diagnose Liver Fibrosis and Cirrhosis | | Liver fibrosis is a dynamic procedure that results from an irregularity between fibrogenesis and fibrolysis. After time this procedure can lead to cirrhosis of the liver |
Metastasis of Cancer Stem Cells Developed in the Microenvironment of Hepatocellular Carcinoma | | Metastasis develops when cancer cells spread from the primary site of a malignant tumor to the surrounding and distant tissues, and it is the most critical problem in cancer treatment |
Method to Convert Stem Cells into Cancer Stem Cells | | The cancer stem cell (CSC) hypothesis suggests that tumors are sustained exclusively by a small population of the cells with stem cell properties |
HEMATOPOIETIC LIKE CELLS DERIVED FROM CANCER STEM CELLS GENERATED FROM MOUSE INDUCED PLURIPOTENT STEM CELLS: NOVEL CONCEPT FOR CANCER ASSOCIATED HEMATOPOIESIS: PB1992 | | Cancer stem cells (CSCs) represent the subpopulation of cancer cells with plasticity to differentiate into other cell phenotypes |
Targeting Ovarian Cancer Cells Overexpressing CD44 with Immunoliposomes Encapsulating Glycosylated Paclitaxel | | Paclitaxel (PTX) is one of the front-line drugs approved for the treatment of ovarian cancer. However, the application of PTX is limited due to the significant hydrophobicity and poor pharmacokinetics |
Generation of Hepatocellular Carcinoma Cancer Stem Cell from induced Pluripotent Stem Cells | | |
Non-mutagenic Chemical Compounds enhance the Conversion of iPSCs into CSCs | | |
Development of Paclitaxel Glycoside Liposomes Conjugated with Anti-CD44 Antibody Targeting Ovarian Cancer Cells | | |
Exogenous Cripto-1 Suppresses Self-Renewal of Cancer Stem Cell Model | | |
Method to Convert Stem Cells into Cancer Stem Cells | The cancer stem cell (CSC) hypothesis suggests that tumors are sustained exclusively by a small population of the cells with stem cell properties | |
Serum ferritin and transferrin as biomarkers for liver fibrosis appreciated using transient hepatic elastography (TE) by fibro scan in egyptian patients with chronic hepatitis C virus | | Exact determination of liver fibrosis stage in chronic hepatitis C patients is of great importance for estimation of anticipation, as well as for evidence of antiviral treatment |